Cluster virus genomic sequences

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Vclust aligns virus (meta)genomic sequences, computes Average Nucleotide Identity (ANI), and clusters virus genomes.

How Vclust works?

Reduces the number of potential genome pairs to align to only those with sufficient k-mer-based sequence similarity.

Performs pairwise sequence alignments and compute ANI measures between genome pairs identified by the pre-alignment filter.

Clusters genomes into putative species and genera clusters according to the International Committee on Taxonomy of Viruses (ICTV) thresholds